Control device Patent

Device for controlling rotary potentiometer mounted on aircraft steering wheel or aileron contro

Thumb-actuated control device

Rotary potentiometer device on the spoke of an aircraft steering wheel provides servo control of certain flight characteristics with no visual attention and a minimum of operational movement

Post-Oligarchic Evolution of Protoplanetary Embryos and the Stability of Planetary Systems

We investigate the orbit-crossing time (T_c) of protoplanet systems both with and without a gas-disk background. The protoplanets are initially with equal masses and separation (EMS systems) scaled by their mutual Hill's radii. In a gas-free environment, we find log (T_c/yr) = A+B \log (k_0/2.3). Through a simple analytical approach, we demonstrate that the evolution of the velocity dispersion in an EMS system follows a random walk. The stochastic nature of random-walk diffusion leads to (i) an increasing average eccentricity ~ t^1/2, where t is the time; (ii) Rayleigh-distributed eccentricities (P(e,t)=e/\sigma^2 \exp(-e^2/(2\sigma^2)) of the protoplanets; (iii) a power-law dependence of T_c on planetary separation. As evidence for the chaotic diffusion, the observed eccentricities of known extra solar planets can be approximated by a Rayleigh distribution. We evaluate the isolation masses of the embryos, which determine the probability of gas giant formation, as a function of the dust and gas surface densities.Comment: 15 pages, 13 figures (2 color ones), accepted for publication in Ap

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor.

Rocaglamide A (RocA) typifies a class of protein synthesis inhibitors that selectively kill aneuploid tumour cells and repress translation of specific messenger RNAs. RocA targets eukaryotic initiation factor 4A (eIF4A), an ATP-dependent DEAD-box RNA helicase; its messenger RNA selectivity is proposed to reflect highly structured 5' untranslated regions that depend strongly on eIF4A-mediated unwinding. However, rocaglate treatment may not phenocopy the loss of eIF4A activity, as these drugs actually increase the affinity between eIF4A and RNA. Here we show that secondary structure in 5' untranslated regions is only a minor determinant for RocA selectivity and that RocA does not repress translation by reducing eIF4A availability. Rather, in vitro and in cells, RocA specifically clamps eIF4A onto polypurine sequences in an ATP-independent manner. This artificially clamped eIF4A blocks 43S scanning, leading to premature, upstream translation initiation and reducing protein expression from transcripts bearing the RocA-eIF4A target sequence. In elucidating the mechanism of selective translation repression by this lead anti-cancer compound, we provide an example of a drug stabilizing sequence-selective RNA-protein interactions

Hadron spectroscopy and static quark potential in full QCD: A comparison of improved actions on the CP-PACS

We present first results from a full QCD calculation on the CP-PACS, comparing various actions at $a^{-1} \sim 1 GeV$ and $m_\pi/m_\rho \approx 0.7$--0.9. We use the plaquette and a renormalization group improved action for the gluons, and the Wilson and the SW-Clover action for quarks. We find that significant improvements in the hadron spectrum results from improving the quarks, while the gluon improvement is required for a rotationally invariant static potential. An ongoing effort towards exploring the chiral limit in full QCD is described.Comment: 6 pages, based on talks presented by R. Burkhalter and T. Kaneko at Lattice97, Edinburg

Phase structure of lattice QCD for general number of flavors

We investigate the phase structure of lattice QCD for the general number of flavors in the parameter space of gauge coupling constant and quark mass, employing the one-plaquette gauge action and the standard Wilson quark action. Performing a series of simulations for the number of flavors $N_F=6$--360 with degenerate-mass quarks, we find that when $N_F \ge 7$ there is a line of a bulk first order phase transition between the confined phase and a deconfined phase at a finite current quark mass in the strong coupling region and the intermediate coupling region. The massless quark line exists only in the deconfined phase. Based on these numerical results in the strong coupling limit and in the intermediate coupling region, we propose the following phase structure, depending on the number of flavors whose masses are less than $\Lambda_d$ which is the physical scale characterizing the phase transition in the weak coupling region: When $N_F \ge 17$, there is only a trivial IR fixed point and therefore the theory in the continuum limit is free. On the other hand, when $16 \ge N_F \ge 7$, there is a non-trivial IR fixed point and therefore the theory is non-trivial with anomalous dimensions, however, without quark confinement. Theories which satisfy both quark confinement and spontaneous chiral symmetry breaking in the continuum limit exist only for $N_F \le 6$.Comment: RevTeX, 20 pages, 43 PS figure